Core Technology Platform
Four Core Technology Platforms
Enzyme Discovery
The technology begins at its source: screening a database for candidate enzymes with specific catalytic functions, then evaluating their activity, stability, and specificity to lay a critical foundation.
Genetic Engineering
Through directed evolution and design, the selected enzymes are optimized at the molecular level to enhance their activity, stability, and catalytic efficiency — meeting the demands of industrial-scale production.
Fermentation Production
Genetically engineered strains are cultured at high density in a controlled environment. Through precise regulation of temperature, pH, dissolved oxygen, and nutrient supply, efficient expression and large-scale production of the target enzyme protein are achieved.
Industrial Application
Enzyme preparations are introduced into the production line. Through immobilized or free enzymatic reaction, affordable substrates are efficiently converted into high-value-added target products — enabling low-cost, eco-friendly, large-scale manufacturing.
Why the World's Top Institutions and Consumers Choose GeneHarbor NMN?
01
Leading Technology
Whole Enzymatic Production Chain
GeneHarbor is one of the few companies in the world with a whole enzymatic industry chain and world-leading technology at every major step. Its in vitro enzymatic process features mild reaction conditions, no chemical residues, and purity of up to 99.9%.
02
Patented Technology Across the Full Industry Chain
Original In Vitro Enzyme Production System
Our patented technologies cover every core link of the full industry chain — from enzyme discovery and the development of novel enzyme preparations with new functions, through genetic engineering to enhance catalytic activity and thermostability, to industrial-scale mass production and application.
03
Authoritative Certification
World's First GRAS · First in China to File
The World's first NMN product to receive FDA-standard GRAS safety certification
- GeneHarbor's Yuyao Factory Passes FDA GMP Certification
- The first company in China to have NMN listed in the cosmetics raw materials catalogue
04
The Choice for Research
Trusted by leading research institutions — High-purity β-NMN raw material selected by major research institutions worldwide.
- Harvard Medical School supplier — Provides high-purity β-NMN raw material to Harvard Medical School.
- China's first NMN human clinical trial — 48 subjects, 6 weeks, significant improvement in endurance.
- 20+ publications in leading journals — Including Cell, EMBO Mol Med, and eBioMedicine.
05
Brand Heritage
20+ Years of Enzyme Technology Expertise - Backed by Hong Kong Science Park
- Founded in 2000 — Over 20 years of accumulated expertise in enzyme technology.
- Founder Professor Wang Jun — Inventor or co-inventor of 80+ patents.
Application Areas
Antibiotics
In vitro enzymatic technology offers a new green manufacturing pathway for antibiotic APIs, demonstrating significant advantages in the production of key intermediates for β-lactam antibiotics.
Functional Foods
Provides high-purity, low-cost raw materials for the functional food industry — including glutathione, S-adenosylmethionine (SAMe), and β-NMN — widely used in the development and production of antioxidant, anti-aging, and immune-regulating products.
Chemical Industry
Traditional chemical manufacturing is highly polluting, energy-intensive, and carries safety risks. In vitro enzymatic technology offers a green, efficient biocatalysis solution — enabling highly selective conversion at room temperature and pressure, and significantly reducing energy consumption and waste emissions.
Pharmaceuticals
Applied to the green manufacturing of pharmaceutical intermediates and active ingredients. Through highly specific enzymatic catalysis, it enables precise synthesis — effectively reducing by-products and chemical residues, and providing pharmaceutical companies with high-purity, low-cost raw material solutions.
Industry Partnerships
Over the past decade or more, our products prepared using these novel applications have won wide recognition. The company has now signed cooperation agreements with several leading companies in the antibiotics, functional food, chemical, and pharmaceutical industries.
GeneHarbor not only supplies high-quality products, but also strives to provide partners with customized enzyme technology solutions — turning a dozen-plus viable scientific concepts into widely adopted industrial products with huge market potential.
GeneHarbor Group
Affiliated Companies
Enzyme Design Limited - A benchmark in enzyme protein development and engineering.
About Enzyme Design
NMN Global Alliance Limited - Experts in industry standards and product design.
About NMN Alliance
NAD+ and Aging · The Scientific Consensus
The scientific consensus is that NAD+ levels in the human body decline with age, leading to the functional decline of mitochondria — the "power houses" of cellular energy — which triggers aging, and a wide range of health issues follows.
The Three Core Functions of NAD+
01
Catalyzes 95%+ of Body Energy
Through the cellular TCA cycle, fatty acid β-oxidation, and other pathways, NAD+ provides 95% of the human body's energy. It is indispensable in cellular energy metabolism, oxidative stress regulation, and signaling pathway transmission.
02
DNA Repair
NAD+ is an essential substrate for the DNA repair enzyme PARP, with significant impact on DNA repair, gene expression, cell cycle progression, cell survival, chromosomal reconstruction, and genomic stability.
03
Activates Longevity Proteins
Activates all seven sirtuins (Sirtuins 1–7) in the human body, playing a key role in cellular stress resistance, energy metabolism, prevention of cell mutation, apoptosis, and aging.
NMN and NAD+
NMN (β-Nicotinamide Mononucleotide) is the most direct precursor to NAD+ and a substance that occurs naturally in all living organisms — including humans — as well as in various foods. However, NMN is present in food only in trace amounts, making it impossible to obtain sufficient supplementation through diet alone.
Authoritative Origins
The discovery of NAD+ and NMN's anti-aging effects is the world's first rigorously scientifically validated research finding with significant results. This major discovery was first proposed and proven by the David Sinclair Lab at Harvard Medical School. Professor Sinclair was subsequently named one of TIME magazine's 100 Most Influential People of 2014.
In December 2013, anti-aging authority David Sinclair published in Cell: "NMN rapidly reverses key aging markers by restoring NAD+ levels, returning muscle tissue to a youthful state."
Harvard ExperimentAfter aged mice ingested NMN, which was then converted into NAD+, their cells were successfully repaired. Within 7 days, the biological age of 2-year-old mice was reversed to 6 months (≈20 human years) — a reversal of 40 years.
Authoritative Endorsement · Two Global Recognitions
Certification of Self-Affirmed GRAS
At Christmas 2018, GeneHarbor's NMN became the world's first NMN to receive safety recognition under the U.S. FDA-standard GRAS (Generally Recognized as Safe) program.
Certification Review Panel
- Joanne Slavin — University of Minnesota
- Professor Emeritus George C. Fahey — University of Illinois at Urbana-Champaign
- Dr. Cho — President, NutraSource
In accordance with Title 21 of the Code of Federal Regulations (21 CFR), the panel unanimously agreed that GeneHarbor's NMN product meets the standard of being safe and harmless.
NASA Recognition
Activating the Source of Youth — Beyond Anti-Aging
NMN's ability to defend against toxins, radiation, and DNA damage has also been recognized by NASA (the U.S. National Aeronautics and Space Administration).
NASA plans to use it to help astronauts withstand cosmic radiation and reduce cell mutations caused by DNA damage.
In 2017, research began into using it to protect astronauts from cosmic ray damage.
DNA damage to astronauts from high-energy particle radiation during a round trip to Mars can cause:
- Death of 5% of the body's cells
- Significant aging
- Severe consequences from cell mutation in nearly 100% of cases
NMN is expected to be a key solution to this challenge.
Certification of Self-Affirmed GRAS
At Christmas 2018, GeneHarbor's NMN became the world's first NMN to receive safety recognition under the U.S. FDA-standard GRAS (Generally Recognized as Safe) program.
Certification Review Panel
- Joanne Slavin — University of Minnesota
- Professor Emeritus George C. Fahey — University of Illinois at Urbana-Champaign
- Dr. Cho — President, NutraSource
In accordance with Title 21 of the Code of Federal Regulations (21 CFR), the panel unanimously agreed that GeneHarbor's NMN product meets the standard of being safe and harmless.
NASA Recognition
Activating the Source of Youth — Beyond Anti-Aging
NMN's ability to defend against toxins, radiation, and DNA damage has also been recognized by NASA (the U.S. National Aeronautics and Space Administration).
NASA plans to use it to help astronauts withstand cosmic radiation and reduce cell mutations caused by DNA damage.
In 2017, research began into using it to protect astronauts from cosmic ray damage.
DNA damage to astronauts from high-energy particle radiation during a round trip to Mars can cause:
- Death of 5% of the body's cells
- Significant aging
- Severe consequences from cell mutation in nearly 100% of cases
NMN is expected to be a key solution to this challenge.
四大核心技術平臺
Enzyme Discovery
显微镜下的酶晶体 / 科研人员筛选酶种
Genetic Engineering
基因测序仪 / DNA双螺旋结构视觉
Fermentation Production
发酵罐实景 / 生产线照片
Industrial Application
工廠車間 / 產品包裝線
Enzyme Discovery
显微镜下的酶晶体 / 科研人员筛选酶种
Genetic Engineering
基因测序仪 / DNA双螺旋结构视觉
Fermentation Production
发酵罐实景 / 生产线照片
Industrial Application
工廠車間 / 產品包裝線
四大核心技術平臺優勢
Why the World's Top Institutions and Consumers Choose GeneHarbor NMN?
技術領先：全球唯一完整酵素製劑產業鏈
基因港是全球唯一一家具備完整酵素製劑產業鏈，並在所有主要步驟中擁有世界領先技術的公司。體外酵素反應條件溫和，無化學殘留，純度達99.9%。
01
成本革命：售價僅為同類產品的1/20
旨透過體外酵素法技術，基因港將NMN生產成本大幅降低。六年前，同類日本產品售價約29,000港元，基因港僅約1,500港元。
02
權威認證：全球首家GRAS + 國內首家備案
The World's first NMN product to receive FDA-standard GRAS safety certification
- 基因港餘姚工廠通過FDA GMP認證
- The first company in China to have NMN listed in the cosmetics raw materials catalogue
03
科學研究驗證：哈佛原料商 + 首個人體臨床試驗
長期為哈佛大學醫學院提供高純度β-NMN原料
- China's first NMN human clinical trial — 48 subjects, 6 weeks, significant improvement in endurance.
- 20+ publications in leading journals — Including Cell, EMBO Mol Med, and eBioMedicine.
04
品牌沉澱：20+年專注酵素技術，香港科學園背書
- 成立於2000年，超過20年酵素技術累積
- 總部及研發中心位於香港科學園區
- 創辦人王駿教授擁有80+項專利
05
Application Areas
Antibiotics
原料藥製備
Functional Foods
營養補充劑
Chemical Industry
精細化學品合成
Pharmaceuticals
活性藥物成分